I don't use an official C25K app, I used the Ease-into-5K app, which is a little bit different (I'm guessing for copyright reasons) so I did have to pause the podcast during the 3-minute walk after 20 minutes of running. In the actual program, you run 25 straight minutes all week.
I did pretty well during the first 20 minutes though I had a horrible side-stitch. I had to stay focused on my breathing to prevent it from getting even worse. Thankfully it disappeared completely during the 3-minute walk. I am feeling pretty worked out now and know that I must incorporate more circuit training this week to help my stamina.